Technical Assistant in Peptide Synthesis

Project overview

The German Cancer Research Center (DKFZ) is one of the largest cancer research centers in Europe. "Research for a life without cancer" is our mission, and our world-class scientists work together with all employees to achieve this.

We research how cancer develops, identify cancer risk factors, and search for new strategies to prevent people from getting cancer. We develop new methods to diagnose tumors more precisely and treat cancer patients more successfully. Every contribution counts – whether in research, administration, or infrastructure. This makes our daily work so meaningful and exciting.

For our Pre-GMP Peptide Unit in the Clinical Cooperation Unit (KKE) "Applied Tumor Immunology" (Head Prof. Dr. Jager), we are looking for a Technical Assistant (m/f/d) in Peptide Synthesis starting January 2027.

Reference Number:

The KKE "Applied Tumor Immunology" works on the development of individualized immunotherapy strategies, particularly adoptive T-cell therapies. Synthetic peptides are necessary for the analysis of specific T-cell responses, which are produced in our Pre-GMP Peptide Lab. In parallel, the Peptide Unit team is currently establishing GMP-compliant peptide production and quality control for patient application within vaccination studies.

• Heidelberg
• Full-time
• Clinical Cooperation Unit "Applied Tumor Immunology"

Responsibilities

• Working in a chemical-synthetic laboratory and in cleanrooms
• Performing peptide syntheses (Fmoc-SPPS) including purification (preparative RP-HPLC) and characterization (LC-MS) within the scope of process development and later clinical production under GMP
• Participation in the quality management system: creating, checking, and maintaining SOPs, as well as audit-proof documentation according to the principles of Good Laboratory Practice
• Participation in the development and establishment of clinical production steps and aseptic filling
• Assisting with the qualification of devices and equipment, as well as process and cleaning validation
• Maintenance, cleaning, and ensuring the operational readiness of peptide synthesizers and HPLC systems
• Goods receipt, proper storage, and labeling

Requirements

We request a meaningful cover letter. Please specifically refer to your experience in peptide synthesis and – if available – in a regulated/controlled working environment in your application.

Our Offer:

Your Contact Person:

Prof. Dr. Stefan Eichmuller

Phone: -3380

The position is initially limited until December 31, 2028. An extension is possible.

Application deadline: November 24, 2026

Applications by email unfortunately cannot be accepted.

Please also note that we cannot return applications submitted by mail.

Are you interested?

Then become part of the DKFZ and contribute to a life without cancer with us!

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented individuals, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion, and age. People with severe disabilities will be preferred if equally qualified.

Note: We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of measles immunity.

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German Cancer Research Center Im Neuenheimer Feld Heidelberg

• Completed training as a Technical Assistant (CTA, BTA) or Chemical Laboratory Assistant
• Practical experience in the synthesis (Fmoc-SPPS), purification (RP-HPLC), or characterization (LC-MS) of peptides
• Willingness to work in cleanrooms of class C and D
• Experience with careful, audit-proof documentation and working according to SOPs
• Very high level of personal responsibility
• Structured and reliable way of working, as well as a strong sense of quality and responsibility
• Very good German language skills (B2 or higher)
• Excellent framework conditions: state-of-the-art infrastructure and opportunity for international exchange at the highest level
• 30 days of vacation
• Flexible working hours
• Remuneration according to TV-L including company pension and capital-forming benefits
• Possibility of part-time work
• Family-friendly working environment
• Sustainable commuting: Discounted Germany Job Ticket
• Develop your full potential: targeted offers for your personal development foster your talents
• Our company health management offers a holistic program for your well-being

Project details

• Start: flexible
• Location: Heidelberg, Baden-Württemberg, Germany, DE
• Languages: German